Glossary Term: Freeze Substitution


Freeze-substitution is based on rapid freezing of tissues followed by solution (“substitution”) of ice at temperatures well below O°C – for the gentle fixation and dehydration of tissue. Freeze substitution is a process for low temperature dehydration and fixation of rapidly frozen cells that usually takes days to complete.

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Created: 2019-06-24 12:09:38 CDT (-0400)
Last modified: 2019-08-18 15:17:17 CDT (-0400)